Webanhydrous tributylamine (0.6 mL) were injected by a syringe to dissolve tributylammonium pyrophosphate under argon (making Reagent 1). 2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one was dissolved in anhydrous DMF (0.6 mL), then it was transferred to Reagent 1 by another syringe and stirred for 30 minutes under argon (making Reagent 2). WebTributylammonium pyrophosphate used as a phosphorylating reagent: In the synthesis of S′-deoxy-S′-methylphosphonic acid diphosphate along with 1, 1′-carbonyl diimidazole. In the synthesis of gram scale level base-modified ribonucleoside-5′-O-triphosphates.

A GENERAL SYNTHESIS OF NUCLEOSIDES-5′ TRIPHOSPHATES

WebU.S. patent application number 16/646593 was filed with the patent office on 2024-08-27 for n4-modified cytidine nucleotides and their use.The applicant listed for this patent is VILNIUS UNIVERSITY. WebTributylammonium pyrophosphate used as a phosphorylating reagent: In the synthesis of S′-deoxy-S′-methylphosphonic acid diphosphate along with 1, 1′-carbonyl diimidazole. In the … tnt minecraft valentine box

An improved protection-free one-pot chemical synthesis of purine locked …

WebMay 1, 2012 · A facile, straightforward, reliable, and an efficient method for the gram-scale chemical synthesis of both purine deoxynucleotides such as 2 '-deoxyguanosine-5 '-triphosphate (dGTP) and 2 '-deoxyadenosine-5 '-triphosphate (dATP) and pyrimidine deoxynucleotides such as 2 '-deoxycytidine-5 '-triphosphate (dCTP), thymidine-5 ' … WebTributylammonium pyrophosphate. Supplier: SPECTRUM CHEMICAL MFG CORP. Storage Temperature: Low Temperature Freezer (–40°C) MDL Number: MFCD00136019. CAS Number: 5975-18-8. WebJun 6, 2008 · A solution of tributylammonium pyrophosphate (377 mg, 0.80 mmol) and tributylamine (0.13 mL, 0.53 mmol) in DMF (1 mL) was added and stirring was continued at 0°C for additional 10 min. Triethylammonium bicarbonate solution (TEAB, 3 mL of 0.2 M) was added, and the reaction mixture was stirred at rt for 30 min. The latter was lyophilized … penneys childrens clothes