WebDec 15, 2008 · The Lutheran (Lu) and Lu (v13) blood group glycoproteins function as receptors for extracellular matrix laminins. Lu and Lu (v13) are linked to the erythrocyte cytoskeleton through a direct interaction with spectrin. However, neither the molecular basis of the interaction nor its functional consequences have previously been delineated. WebThe Lutheran blood group glycoprotein (Lu), also known as basal cell adhesion molecule (B-CAM), is a transmembrane receptor with five immunoglobulin-like domains in its …
2PF6: Lutheran glycoprotein, N-terminal domains 1 and 2 - RCSB
Webhe Lutheran blood group system (BGS) consists of a large number of antigens, 24 being recognised by the International Society of Blood Transfusion at the time of writing, and is also of interest in terms of the various backgrounds to the (apparent) Lu(a-b-) phenotypes. The Lutheran BGS is also incorrectly named, as will be explained shortly. WebJan 28, 2013 · The Lutheran glycoproteins (CD239) are a pair of isoforms that belong to the immunoglobulin superfamily. Their function is unknown, but they bind the extracellular … donald wayland
Functions of red cell surface proteins - Daniels - 2007 - Vox …
WebThe Lutheran blood group glycoprotein (Lu), an Ig superfamily (IgSF) transmembrane receptor, is also known as basal cell adhesion molecule (B-CAM). Lu/B-CAM is a specific receptor for laminin α5,... WebOct 12, 2024 · The lutheran blood group glycoprotein, another member of the immunoglobulin superfamily, is widely expressed in human tissues and is developmentally regulated in human liver. Proc Natl Acad Sci USA . 1995 ; 92:5496–5500. doi: 10.1073/pnas.92.12.5496 Crossref Medline Google Scholar WebMar 22, 2024 · Lutheran blood group glycoprotein, also designated BCAM cell surface glycoprotein or auberger B antigen, plays a role in intracellular signaling. It is a widely expressed protein but the highest level of expression is in pancreas tissue. For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. donald waugh actor