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Lutheran blood group glycoprotein

WebDec 15, 2008 · The Lutheran (Lu) and Lu (v13) blood group glycoproteins function as receptors for extracellular matrix laminins. Lu and Lu (v13) are linked to the erythrocyte cytoskeleton through a direct interaction with spectrin. However, neither the molecular basis of the interaction nor its functional consequences have previously been delineated. WebThe Lutheran blood group glycoprotein (Lu), also known as basal cell adhesion molecule (B-CAM), is a transmembrane receptor with five immunoglobulin-like domains in its …

2PF6: Lutheran glycoprotein, N-terminal domains 1 and 2 - RCSB

Webhe Lutheran blood group system (BGS) consists of a large number of antigens, 24 being recognised by the International Society of Blood Transfusion at the time of writing, and is also of interest in terms of the various backgrounds to the (apparent) Lu(a-b-) phenotypes. The Lutheran BGS is also incorrectly named, as will be explained shortly. WebJan 28, 2013 · The Lutheran glycoproteins (CD239) are a pair of isoforms that belong to the immunoglobulin superfamily. Their function is unknown, but they bind the extracellular … donald wayland https://smithbrothersenterprises.net

Functions of red cell surface proteins - Daniels - 2007 - Vox …

WebThe Lutheran blood group glycoprotein (Lu), an Ig superfamily (IgSF) transmembrane receptor, is also known as basal cell adhesion molecule (B-CAM). Lu/B-CAM is a specific receptor for laminin α5,... WebOct 12, 2024 · The lutheran blood group glycoprotein, another member of the immunoglobulin superfamily, is widely expressed in human tissues and is developmentally regulated in human liver. Proc Natl Acad Sci USA . 1995 ; 92:5496–5500. doi: 10.1073/pnas.92.12.5496 Crossref Medline Google Scholar WebMar 22, 2024 · Lutheran blood group glycoprotein, also designated BCAM cell surface glycoprotein or auberger B antigen, plays a role in intracellular signaling. It is a widely expressed protein but the highest level of expression is in pancreas tissue. For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. donald waugh actor

CD239 Polyclonal Antibody (BS-7546R) - Thermo Fisher Scientific

Category:Identifying the IgSF domains recognized by anti-Lu/B-CAM

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Lutheran blood group glycoprotein

Vascular laminins in physiology and pathology - ScienceDirect

WebJun 6, 1995 · Glycoproteins expressing the Lutheran blood group antigens were isolated from human erythrocyte membranes and from human fetal liver. Amino acid sequence analyses allowed the design of redundant oligonucleotides that were used to generate a … WebJun 6, 1995 · The Lutheran blood group glycoprotein, another member of the immunoglobulin superfamily, is widely expressed in human tissues and is developmentally regulated in human liver. S F Parsons, G Mallinson, C H Holmes, +6, J M Houlihan, K L Simpson, W J Mawby, N K Spurr, D Warne, A N Barclay, and D J Anstee-6 Authors Info & …

Lutheran blood group glycoprotein

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WebAug 12, 2011 · The Lutheran blood group glycoprotein (Lu), an Ig superfamily (IgSF) transmembrane receptor, is also known as basal cell adhesion molecule (B-CAM). Lu/B … WebApr 4, 2007 · The Lutheran blood group glycoprotein, first discovered on erythrocytes, is widely expressed in human tissues. It is a ligand for the alpha5 subunit of Laminin …

WebMar 29, 2024 · This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. … WebJan 1, 2024 · In addition to the integrin receptors, the non-integrin receptors MCAM (also known as CD146, cell surface glycoprotein MUC18 and melanoma cell adhesion molecule) and Lutheran blood group antigen (also known as basal cell adhesion molecule B-CAM) have been shown to be exclusive receptors for laminin 411 [26] and laminin 511, [27], …

WebOn RBCs, Lutheran glycoprotein may be involved in the adherence of RBCs to vascular endothelial cells and in the vaso-occlusion that is characteristic of sickle cell disease. 51 … WebThe Lutheran blood group glycoprotein (Lu), an Ig superfamily (IgSF) transmembrane receptor, is also known as basal cell adhesion molecule (B-CAM). Lu/B-CAM is a specific receptor for laminin α5 ...

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WebNational Center for Biotechnology Information city of brentwood parks and recreationWebLutheran blood group glycoprotein is a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five, N-terminus, extracellular immunoglobulin domains, a single transmembrane domain, and a short, C-terminal cytoplasmic tail. city of brentwood municipal court missouriWebMar 29, 2024 · This gene encodes Lutheran blood group glycoprotein, a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five extracellular immunoglobulin domains, a single transmembrane domain, and a short C-terminal cytoplasmic tail. city of brentwood parks and recWebThe FREE Blood Donor app puts the power to save lives in the palm of your hand. Find nearby Red Cross blood drives, schedule and manage appointments, complete your … donald wayne robinson + texasWebBasal-Cell Adhesion Molecule (BCAM) and Lutheran blood group glycoprotein (LU) are two alternatively spliced variants of a single immunoglobulin superfamily (IgSF) protein that differ in the length of their cytoplasmic tails. BCAM cDNA encodes a 628 amino acid (aa) residues precursor protein with a putative 31 aa signal peptide, a 597 aa ... city of brentwood permitsWebThe Lutheran blood group system consists of human erythrocyte epitopes recognized by alloantibodies against Lua and Lu b products. Antibodies developed against Lutheran antigens during pregnancy may induce hemolytic disease of the newborn. donald w carterWebJan 1, 2001 · The Lutheran blood group is composed of a complex set of antigens expressed on 2 integral membrane glycoprotein isoforms of 85 and 78 kd.1,2 The … donald w blair